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CD51 抗体 (FITC)

This anti-CD51 antibody is a 小鼠 单克隆 antibody detecting CD51 in FACS. Suitable for 人.
产品编号 ABIN371553
发货至: 中国

Quick Overview for CD51 抗体 (FITC) (ABIN371553)

抗原

See all CD51 (ITGAV) 抗体
CD51 (ITGAV) (Integrin alpha V (ITGAV))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD51 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

13C2
  • 产品特性

    Synonyms: Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha

    亚型

    IgG1
  • 应用备注

    Flow Cytometry: 10 μL/10^6 cells.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.09 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD51 (ITGAV) (Integrin alpha V (ITGAV))

    别名

    CD51 / ITGAV

    背景

    Integrin alpha V chain interacts with the integrin beta 3 subunit/CD61 to form the alpha-V-beta-3 heterodimer/vitronectin receptor. It is expressed on endothelial cells, some activated leukocytes, NK cells, macrophages, neutrophils, and platelets. Integrin alpha V also forms heterodimers with the integrin beta 1, beta 5, beta 6, and beta 8 subunits. Alpha-V-beta-3 is an activation dependent receptor for platelet attachment and spreading on vitronectin and other matrix components. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. Alpha-V/beta-6 binds to foot-and-mouth disease virus (FMDV) VP1 protein and acts as a receptor for this virus By similarity. Alpha-V/beta-6 binds to coxsackievirus A9 and coxsackievirus B1 capsid proteins and acts as a receptor for these viruses. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31. (Ref.1-4)Synonyms: Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha

    UniProt

    P06756

    途径

    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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