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ITGA5 抗体 (PE)

This anti-ITGA5 antibody is a 大鼠 单克隆 antibody detecting ITGA5 in FACS. Suitable for 小鼠.
产品编号 ABIN370978
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ITGA5 抗体 (PE) (ABIN370978)

抗原

See all ITGA5 抗体
ITGA5 (Integrin, alpha 5 (ITGA5))

适用

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  • 80
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小鼠

宿主

  • 100
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大鼠

克隆类型

  • 78
  • 63
单克隆

标记

  • 69
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  • 3
  • 3
  • 3
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  • 3
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
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This ITGA5 antibody is conjugated to PE

应用范围

  • 87
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Flow Cytometry (FACS)

克隆位点

5H10-27
  • 产品特性

    Synonyms: Integrin alpha-5, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5, VLA5, FNRA,CD49 antigen-like family member E

    免疫原

    C57BL/6 x A/J F1 mouse mast cell line MC/9. (Ref. 1)

    亚型

    IgG2a
  • 应用备注

    Flow Cytometry: . < / = 0.3 μg/10^6 cells.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS containing 0.09 % Sodium Azide as preservative and a stabilizing agent.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    ITGA5 (Integrin, alpha 5 (ITGA5))

    别名

    CD49e / ITGA5

    背景

    Integrin alpha 5 belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post translational cleavage in the extracellular domain to yield disulfide linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell surface mediated signalling. It is expressed on thymocytes, activated T cells, mast cells, and a variety of mouse cell lines. Soluble 5H10-27 antibody inhibits VLA-5-mediated functions in vitro. (Ref.1,2-4,6) Immobilized 5H10-27 has also been demonstrated to co-stimulate the proliferative response of CD8+ T cells to plate-bound anti-CD3 monoclonal antibody. (Ref.3)Synonyms: CD49 antigen-like family member E, FNRA, Fibronectin receptor subunit alpha, Integrin alpha-5, Integrin alpha-F, VLA-5, VLA5

    UniProt

    P11688

    途径

    Integrin Complex
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