ITGA5 抗体 (PE)
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北京 101111
Quick Overview for ITGA5 抗体 (PE) (ABIN370978)
抗原
See all ITGA5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Synonyms: Integrin alpha-5, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5, VLA5, FNRA,CD49 antigen-like family member E
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免疫原
- C57BL/6 x A/J F1 mouse mast cell line MC/9. (Ref. 1)
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亚型
- IgG2a
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应用备注
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Flow Cytometry: . < / = 0.3 μg/10^6 cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS containing 0.09 % Sodium Azide as preservative and a stabilizing agent.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- ITGA5 (Integrin, alpha 5 (ITGA5))
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别名
- CD49e / ITGA5
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背景
- Integrin alpha 5 belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post translational cleavage in the extracellular domain to yield disulfide linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell surface mediated signalling. It is expressed on thymocytes, activated T cells, mast cells, and a variety of mouse cell lines. Soluble 5H10-27 antibody inhibits VLA-5-mediated functions in vitro. (Ref.1,2-4,6) Immobilized 5H10-27 has also been demonstrated to co-stimulate the proliferative response of CD8+ T cells to plate-bound anti-CD3 monoclonal antibody. (Ref.3)Synonyms: CD49 antigen-like family member E, FNRA, Fibronectin receptor subunit alpha, Integrin alpha-5, Integrin alpha-F, VLA-5, VLA5
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UniProt
- P11688
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途径
- Integrin Complex
抗原
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