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CD40 Ligand 抗体 (PE)

This anti-CD40 Ligand antibody is a 仓鼠 单克隆 antibody detecting CD40 Ligand in FACS. Suitable for 小鼠.
产品编号 ABIN370949
发货至: 中国

Quick Overview for CD40 Ligand 抗体 (PE) (ABIN370949)

抗原

See all CD40 Ligand (CD40LG) 抗体
CD40 Ligand (CD40LG)

适用

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小鼠

宿主

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仓鼠

克隆类型

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单克隆

标记

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This CD40 Ligand antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

MR1
  • 产品特性

    Synonyms: CD40 ligand, CD40-L, CD40LG, TNFSF5, TRAP, GP39, Tumor necrosis factor ligandsuperfamily member 5, TNF-related activation protein, T-cell antigen Gp39

    亚型

    IgG
  • 应用备注

    Flow Cytometry: < / 2 μg/10^6 cells. (Ref.1,5)
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS containing 0.09 % Sodium Azide as preservative and a stabilizing agent.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD40 Ligand (CD40LG)

    别名

    CD154 / CD40L

    背景

    CD154, formerly known as CD40 ligand and gp39, is a type II integral membrane protein and a member of the tumor necrosis factor (TNF) family of ligands. (Ref.1-7) It is an important accessory molecule in T cell-B cell costimulatory interactions, and is expressed predominantly on activated CD4+ T lymphocytes. It is also present on the surface of activated Th0, Th1, and Th2 T cell clones. Its expression is transient and cyclosporinsensitive. (Ref.6) The MR1 monoclonal antibody binds to murine CD154 with high affinity, blocks binding to CD40, and blocks CD154 function. (Ref.1,5) Administration of this antibody to mice blocks the ability to mount primary and secondary immune responses to TD antigens, yet does not alter the immune response to TI antigens. (Ref.4)Synonyms: CD40 ligand, CD40-L, CD40LG, GP39, T-cell antigen Gp39, TNF-related activation protein, TNFSF5, TRAP, Tumor necrosis factor ligand superfamily member 5

    UniProt

    P27548

    途径

    NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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