EPAS1 抗体 (C-Term)
Quick Overview for EPAS1 抗体 (C-Term) (ABIN363383)
抗原
See all EPAS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Reacts with mouse, rat, fish and human HIF-2 alpha
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交叉反应 (详细)
- Does not cross-react with HIF-1 alpha.
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纯化方法
- Antigen affinity purified
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免疫原
- Synthetic peptide derived from the C-term domain of mouse/human HIF-2 alpha protein.
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB1.0 μg/mL - 2.0 μg/mL ChIP1:10-1:500 ELISA 1:100-1:2000 ICC/IF1:100 IHC 1:100 IP5 μg/1 mg lysate -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, Sodium azide 0.05 %
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 4°C. Do not freeze.
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- EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))
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别名
- Hypoxia-Inducible Factor 2-alpha
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背景
- Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung.
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基因ID
- 2034
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途径
- Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect
抗原
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