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Integrin beta 3 抗体 (AA 783-787)

Name: Integrin beta 3 抗体 (AA 783-787)
SKU: ABIN362976
Availability: OutOfStock

ITGB3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated

(1 reference)

产品编号 ABIN362976

发货至: 中国

Datasheet as PDF

抗原 See all Integrin beta 3 (ITGB3) 抗体

Integrin beta 3 (ITGB3)
抗原表位
20

16

15

13

8

6

5

4

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 783-787
适用
171

86

50

16

15

13

12

10

8

7

5

2

2

2

1

1

1

1
人, 小鼠
宿主
114

60

8

2
兔
Compatible Secondaries
克隆类型
110

72
多克隆
标记
93

16

12

10

7

5

3

3

3

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This Integrin beta 3 antibody is un-conjugated
应用范围
122

78

51

49

26

25

22

18

15

13

12

5

5

3

3

3

2

1

1

1
Western Blotting (WB)

特异性

The antibody detects endogenous level of total Integrin b3 protein.

纯化方法

The antibody was affinity-purified from rabbit antiserum by affinity-chromatographyusing epitope-specific immunogen.

免疫原

Peptide sequence around AA 783-787 (I-T-Y-R-G) derived from Human Integrin B3, ITGB3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

亚型

IgG

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anti-Integrin beta 3 (ITGB3) (AA 134-376) antibody
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anti-Integrin beta 3 (ITGB3) antibody
ITGB3 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated

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anti-Integrin beta 3 (ITGB3) (AA 385-490) antibody
ITGB3 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal ITGB3-2145 unconjugated

anti-Integrin beta 3 (ITGB3) antibody (FITC)
ITGB3 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal VIPL2 FITC

anti-Integrin beta 3 (ITGB3) antibody (PerCP)
ITGB3 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal VIPL2 PerCP

anti-Integrin beta 3 (ITGB3) (AA 610-718) antibody
ITGB3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Integrin beta 3 (ITGB3) (AA 734-760) antibody
ITGB3 适用: 人 WB, FACS, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Integrin beta 3 (ITGB3) (AA 135-377) antibody
ITGB3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blotting: 1:500-1:1000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C/-20 °C

储存方法

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Wang, Bi, Ampah, Zhang, Li, Jiao, Wang, Ba, Zeng: "Lipid raft regulates the initial spreading of melanoma A375 cells by modulating ?1 integrin clustering." in: The international journal of biochemistry & cell biology, Vol. 45, Issue 8, pp. 1679-89, (2013) (PubMed).
抗原

Integrin beta 3 (ITGB3)

别名

Integrin beta3 (ITGB3 产品)

别名

BDPLT16 antibody, BDPLT2 antibody, CD61 antibody, GP3A antibody, GPIIIa antibody, GT antibody, INGRB3 antibody, integrin antibody, INTB3 antibody, GPIIIA antibody, cd61 antibody, gp3a antibody, itgb3 antibody, itgb3.2 antibody, itgb3.1 antibody, integrin subunit beta 3 antibody, integrin beta 3 antibody, integrin subunit beta 3 L homeolog antibody, integrin beta 3a antibody, integrin beta 3b antibody, ITGB3 antibody, Itgb3 antibody, itgb3.L antibody, itgb3a antibody, itgb3b antibody

背景

The Itg-Beta3 gene encodes the beta subunit of the platelet membrane adhesive protein receptor complex Itg-Beta3 protein, which belongs to the Integrin class of cell adhesion molecule receptors that share a common heterotrimeric structure with a and Beta subunits. It is a common Beta subunit of the platelet complex and of two other Integrins (Fibronectin and Vitronectin Receptors), which have distinct a subunits. Itg-Beta3 has been implicated in a wide variety of functions, including platelet aggregation and thrombosis and implantation, placentation, angiogenesis, bone remodeling, and tumor progression. Glanzmann Thrombasthenia can result from defects in the genes for either the Itg-a2B or the Itg-Beta3 subunit

分子量

110 kDa

NCBI登录号

NP_000203

UniProt

P05106

途径

Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex