PRKAA1/PRKAA2 抗体 (AA 170-174, AA 172-176)
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Quick Overview for PRKAA1/PRKAA2 抗体 (AA 170-174, AA 172-176) (ABIN362825)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 170-174, AA 172-176
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特异性
- The antibody detects endogenous level of total AMPKa1/AMPKa2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
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免疫原
- Peptide sequence around AA 172-176, 170-174 (L-R-T-S-C) derived from Human AMPKa1, AMPKa2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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亚型
- IgG
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anti-AMPK1/AMPK2 (pThr172), (pThr183) antibody
适用: 人, 小鼠, 大鼠, 猴 WB, IF, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-AMPK1/AMPK2 (pThr172), (pThr183) antibody适用: 人, 小鼠, 大鼠, Pig, 绵羊 WB, ELISA, IF (cc), IHC (p), FACS, IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-AMPK1/AMPK2 (pThr172), (pThr183) antibody (Cy7)适用: 人, 小鼠, 大鼠, Pig, 绵羊 WB, IF (cc), FACS, IF (p) 宿主: 兔 Polyclonal Cy7
anti-AMPK1/AMPK2 (AA 14-47), (N-Term) antibody适用: 小鼠 WB 宿主: 兔 Polyclonal RB43852 unconjugated
anti-AMPK1/AMPK2 (Ser1071) antibody适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-AMPK1/AMPK2 (Catalytic Domain), (N-Term) antibody适用: 人, 小鼠, 大鼠, Drosophila melanogaster, Vertebrate WB, IF, ELISA, IHC (fro), IP 宿主: 小鼠 Monoclonal 84-1 unconjugated
anti-AMPK1/AMPK2 (pThr172), (pThr183) antibody适用: 人, 小鼠, 大鼠, Pig, 猴, Penaeus japonicus WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-AMPK1/AMPK2 (Center) antibody适用: 人, 小鼠, 大鼠, Pig, 小鸡 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-AMPK1/AMPK2 (pThr172), (pThr183) antibody适用: 人, 小鼠, 大鼠, Pig, 小鸡 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- PRKAA1/PRKAA2 (AMPK1/AMPK2)
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别名
- AMPKalpha1/AMPKalpha2
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背景
- Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.
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分子量
- 63 kDa
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NCBI登录号
- NP_006243, NP_006242
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UniProt
- Q13131
抗原
-
