SMC1A 抗体 (AA 955-959)
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Quick Overview for SMC1A 抗体 (AA 955-959) (ABIN362824)
抗原
See all SMC1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 955-959
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特异性
- The antibody detects endogenous level of total SMC1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Peptide sequence around AA 955-959 (G-S-S-Q-G) derived from Human SMC1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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亚型
- IgG
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anti-Structural Maintenance of Chromosomes 1A (SMC1A) antibody
KD Validated SMC1A 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2670 unconjugated Recombinant Antibody
anti-Structural Maintenance of Chromosomes 1A (SMC1A) antibodySMC1A 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5B6 unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (pSer957) antibodySMC1A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (pSer957) antibodySMC1A 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) antibodySMC1A 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 8C11 unconjugated Recombinant Antibody
anti-Structural Maintenance of Chromosomes 1A (SMC1A) antibodySMC1A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (AA 366-465) antibodySMC1A 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B9 unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (C-Term) antibodySMC1A 适用: 人 WB, IP, ChIP-seq 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (N-Term) antibodySMC1A 适用: 人 WB, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (C-Term) antibodySMC1A 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))
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别名
- SMC1
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背景
- Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, or via its phosphorylation by ATR. Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint.
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分子量
- 145 kDa
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NCBI登录号
- NP_006297
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UniProt
- Q14683
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途径
- Stem Cell Maintenance
抗原
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