电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CDKN1B 抗体 (AA 8-12)

This anti-CDKN1B antibody is a 兔 多克隆 antibody detecting CDKN1B in WB 和 IHC. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN362757
发货至: 中国

Quick Overview for CDKN1B 抗体 (AA 8-12) (ABIN362757)

抗原

See all CDKN1B 抗体
CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))

适用

  • 281
  • 131
  • 118
  • 34
  • 7
  • 6
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 236
  • 59
  • 2
  • 1
  • 1

克隆类型

  • 225
  • 74
多克隆

标记

  • 155
  • 20
  • 16
  • 13
  • 13
  • 11
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This CDKN1B antibody is un-conjugated

应用范围

  • 201
  • 128
  • 76
  • 70
  • 58
  • 41
  • 38
  • 32
  • 26
  • 16
  • 16
  • 14
  • 7
  • 7
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 34
    • 21
    • 21
    • 19
    • 16
    • 12
    • 11
    • 9
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 8-12

    特异性

    The antibody detects endogenous level of total p27Kip1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Peptide sequence around AA 8-12 (N-G-S-P-S) derived from Human p27Kip1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

    亚型

    IgG
  • 应用备注

    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Yang, Xu, Li, Duan, Fu, Zhang, Zhao, Qiao, Chen, Geng, Che, Cao, Wang, Zhang, Long, He, Cui, Chen, Wang, Liu: "Cloning and characterization of a novel intracellular protein p48.2 that negatively regulates cell cycle progression." in: The international journal of biochemistry & cell biology, Vol. 41, Issue 11, pp. 2240-50, (2009) (PubMed).

  • 抗原

    CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))

    别名

    p27Kip1

    背景

    Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events.

    分子量

    27 kDa

    NCBI登录号

    NP_004055

    UniProt

    P46527

    途径

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Sensory Perception of Sound, Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Autophagy
You are here:
Chat with us!