电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

JAK1 抗体 (AA 1020-1024)

Cited in 1 publication. This 兔 多克隆 anti-JAK1 antibody specifically detects JAK1 in WB 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN362702
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for JAK1 抗体 (AA 1020-1024) (ABIN362702)

抗原

See all JAK1 抗体
JAK1 (Janus Kinase 1 (JAK1))

适用

  • 119
  • 87
  • 64
  • 2
  • 2
  • 2
  • 2
人, 小鼠, 大鼠

宿主

  • 98
  • 25
  • 1
  • 1

克隆类型

  • 77
  • 48
多克隆

标记

  • 56
  • 8
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
This JAK1 antibody is un-conjugated

应用范围

  • 94
  • 45
  • 29
  • 19
  • 17
  • 17
  • 17
  • 14
  • 11
  • 9
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 26
    • 26
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1020-1024

    特异性

    The antibody detects endogenous level of total JAK1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Peptide sequence around AA 1020-1024 (K-E-Y-Y-T) derived from Human JAK1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

    亚型

    IgG
  • 应用备注

    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Liu, Huang, Zeng, Chen, Huang, Guo, Liu, Xu, Mo, Li: "Down-regulation of JAK1 by RNA interference inhibits growth of the lung cancer cell line A549 and interferes with the PI3K/mTOR pathway." in: Journal of cancer research and clinical oncology, Vol. 137, Issue 11, pp. 1629-40, (2011) (PubMed).

  • 抗原

    JAK1 (Janus Kinase 1 (JAK1))

    别名

    JAK1

    背景

    Tyrosine kinase of the non-receptor type, involved in the IFN-a/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.

    分子量

    130 kDa

    NCBI登录号

    NP_002218

    UniProt

    P23458

    途径

    JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response
You are here:
Chat with us!