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Nibrin 抗体 (AA 341-345)

This anti-Nibrin antibody is a 兔 多克隆 antibody detecting Nibrin in WB 和 IHC. Suitable for 人.
产品编号 ABIN362592
发货至: 中国

Quick Overview for Nibrin 抗体 (AA 341-345) (ABIN362592)

抗原

See all Nibrin (NBN) 抗体
Nibrin (NBN)

适用

  • 94
  • 61
  • 35
  • 2
  • 1
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宿主

  • 111
  • 15

克隆类型

  • 98
  • 28
多克隆

标记

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This Nibrin antibody is un-conjugated

应用范围

  • 104
  • 42
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  • 22
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  • 15
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 39
    • 15
    • 10
    • 8
    • 4
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    AA 341-345

    特异性

    The antibody detects endogenous level of total p95/NBS1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Peptide sequence around AA 341-345 (S-L-S-Q-G) derived from Human p95, NBS1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

    亚型

    IgG
  • 应用备注

    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    Nibrin (NBN)

    别名

    p95/NBS1

    背景

    Mutations in p95/NBS1 gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

    分子量

    95 kDa

    NCBI登录号

    NP_002476

    UniProt

    O60934

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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