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BIM 抗体 (pSer69)

This 兔多克隆 antibody specifically detects BIM in IHC 和 IF. It exhibits reactivity toward 人, 小鼠和大鼠.

产品编号 ABIN362371

发货至: 中国

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Quick Overview for BIM 抗体 (pSer69) (ABIN362371)

抗原

See all BIM (BCL2L11) 抗体

BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This BIM antibody is un-conjugated

应用范围

Immunohistochemistry (IHC), Immunofluorescence (IF)

Discover our top product BCL2L11 Primary Antibody

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pSer69

特异性

The antibody detects endogenous level of BIM only when phosphorylated at serine 69.

纯化方法

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.

免疫原

Peptide sequence around phosphorylation site of pSer69 (P-A-S (p) -P-G) derived from Human BIM. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

亚型

IgG
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 2-120) antibody
BCL2L11 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 134-160) antibody
BCL2L11 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22105 unconjugated

anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (pSer87) antibody
BCL2L11 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (C-Term) antibody
BCL2L11 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 130-165) antibody
BCL2L11 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB00963 unconjugated

anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 1-198) antibody
BCL2L11 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) antibody
KO Validated BCL2L11 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB610 unconjugated Recombinant Antibody

anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 51-150) antibody
BCL2L11 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (pSer69) antibody
BCL2L11 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (pSer77) antibody
BCL2L11 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C/-20 °C

储存方法

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
抗原

BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

别名

BIM

背景

Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-a1, isoform Bim-a2 and isoform Bim-a3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS.

分子量

23 kDa

NCBI登录号

NP_006529

UniProt

O43521

途径

PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity