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HDAC2 抗体 (pSer394)

This anti-HDAC2 antibody is a 兔 多克隆 antibody detecting HDAC2 in WB, IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN362214
发货至: 中国

Quick Overview for HDAC2 抗体 (pSer394) (ABIN362214)

抗原

See all HDAC2 抗体
HDAC2 (Histone Deacetylase 2 (HDAC2))

适用

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人, 小鼠, 大鼠

宿主

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  • 14
  • 3
  • 1

克隆类型

  • 102
  • 31
多克隆

标记

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This HDAC2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 29
    • 15
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    • 7
    • 5
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    • 4
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    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
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    pSer394

    特异性

    The antibody detects endogenous level of HDAC2 only when phosphorylated at serine 394.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

    免疫原

    Peptide sequence around phosphorylation site of pSer394 (E-D-S (p) -G-D) derived from Human HDAC2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

    亚型

    IgG
  • 应用备注

    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Immunofluorescence: 1:100-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    HDAC2 (Histone Deacetylase 2 (HDAC2))

    别名

    HDAC2

    背景

    Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes

    分子量

    60 kDa

    NCBI登录号

    NP_001518

    UniProt

    Q92769

    途径

    Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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