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JAK1 抗体 (pTyr1022)

Name: JAK1 抗体 (pTyr1022)
SKU: ABIN362145
Availability: OutOfStock

This anti-JAK1 antibody is a 兔多克隆 antibody detecting JAK1 in WB 和 IHC. Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 2+ publications.

(2 references)

产品编号 ABIN362145

发货至: 中国

Quick Overview for JAK1 抗体 (pTyr1022) (ABIN362145)

抗原

See all JAK1 抗体

JAK1 (Janus Kinase 1 (JAK1))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This JAK1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product JAK1 Primary Antibody

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pTyr1022

特异性

The antibody detects endogenous level of JAK1 only when phosphorylated at tyrosine 1022.

纯化方法

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.

免疫原

Peptide sequence around phosphorylation site of pTyr1022 (K-E-Y (p) -Y-T) derived from Human JAK1. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

亚型

IgG
anti-Janus Kinase 1 (JAK1) (pTyr1022), (pTyr1023) antibody
JAK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) (pTyr1022) antibody
JAK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) antibody
JAK1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated

anti-Janus Kinase 1 (JAK1) antibody
JAK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) (AA 172-204), (N-Term) antibody
JAK1 适用: 人 WB 宿主: 兔 Polyclonal RB43809 unconjugated

anti-Janus Kinase 1 (JAK1) (AA 866-899), (C-Term) antibody
JAK1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB43812 unconjugated

anti-Janus Kinase 1 (JAK1) (Ser639) antibody
JAK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) (C-Term) antibody
JAK1 适用: 人, 小鼠, 大鼠, 小鸡, 犬, Cow, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) (pTyr1034), (pTyr1035) antibody
JAK1 适用: 人, 小鼠 WB, ELISA, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) (AA 596-841) antibody
JAK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C/-20 °C

储存方法

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Liu, Huang, Zeng, Chen, Huang, Guo, Liu, Xu, Mo, Li: "Down-regulation of JAK1 by RNA interference inhibits growth of the lung cancer cell line A549 and interferes with the PI3K/mTOR pathway." in: Journal of cancer research and clinical oncology, Vol. 137, Issue 11, pp. 1629-40, (2011) (PubMed).

Cha, Moon, Lee, Ahn, Lee, Lee, Fornace, Kim, Cha, Park: "Zap70 functions to maintain stemness of mouse embryonic stem cells by negatively regulating Jak1/Stat3/c-Myc signaling." in: Stem cells (Dayton, Ohio), Vol. 28, Issue 9, pp. 1476-86, (2010) (PubMed).
抗原

JAK1 (Janus Kinase 1 (JAK1))

别名

JAK1

背景

Tyrosine kinase of the non-receptor type, involved in the IFN-a/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.

分子量

130 kDa

NCBI登录号

NP_002218

UniProt

P23458

途径

JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response