Integrin beta 3 抗体 (pTyr773)
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- 抗原 See all Integrin beta 3 (ITGB3) 抗体
- Integrin beta 3 (ITGB3)
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抗原表位
- pTyr773
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Integrin beta 3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- The antibody detects endogenous level of Integrin b3 only when phosphorylated at tyrosine 773.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- 免疫原
- Peptide sequence around phosphorylation site of pTyr773 (P-L-Y (p) -K-E) derived from Human Integrin b3. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- 亚型
- IgG
- Top Product
- Discover our top product ITGB3 Primary Antibody
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anti-Integrin beta 3 (ITGB3) (AA 27-120) antibody
ITGB3 适用: 人, 小鼠 WB, FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 (ITGB3) (AA 134-376) antibodyITGB3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 (ITGB3) antibodyITGB3 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Integrin beta 3 (ITGB3) (AA 27-179) antibodyITGB3 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 3E8A6 unconjugated
anti-Integrin beta 3 (ITGB3) (AA 385-490) antibodyITGB3 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal ITGB3-2145 unconjugated
anti-Integrin beta 3 (ITGB3) antibody (FITC)ITGB3 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal VIPL2 FITC
anti-Integrin beta 3 (ITGB3) antibody (PerCP)ITGB3 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal VIPL2 PerCP
anti-Integrin beta 3 (ITGB3) (AA 610-718) antibodyITGB3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 (ITGB3) (AA 734-760) antibodyITGB3 适用: 人 WB, FACS, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 (ITGB3) (AA 135-377) antibodyITGB3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- 抗原
- Integrin beta 3 (ITGB3)
- 别名
- Integrin beta3 (ITGB3 产品)
- 背景
- Integrin a-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin a-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins a-IIb/beta-3 and a-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin a-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin a-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
- 分子量
- 110 kDa
- NCBI登录号
- NP_000203
- UniProt
- P05106
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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