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TAO Kinase 2 抗体 (pSer181)

TAOK2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN361519
发货至: 中国
  • 抗原 See all TAO Kinase 2 (TAOK2) 抗体
    TAO Kinase 2 (TAOK2)
    抗原表位
    • 8
    • 6
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    pSer181
    适用
    • 36
    • 14
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 34
    • 2
    克隆类型
    • 34
    • 2
    多克隆
    标记
    • 16
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TAO Kinase 2 antibody is un-conjugated
    应用范围
    • 24
    • 18
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    Specific for the ~120k TAO2 phosphorylated at Ser181 in Western blots. Immunolabeling is completely eliminated by treatment with phosphatase.
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    canine, finch, Xenopus, zebrafish
    纯化方法
    Antigen Affinity Purified from Pooled Serum
    免疫原
    Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser181 conjugated to KLH
    Top Product
    Discover our top product TAOK2 Primary Antibody
  • 应用备注
    Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
    储存条件
    -20 °C
  • 抗原
    TAO Kinase 2 (TAOK2)
    别名
    TAOK2 (TAOK2 产品)
    别名
    MAP3K17 antibody, PSK antibody, PSK1 antibody, PSK1-BETA antibody, TAO1 antibody, TAO2 antibody, Tao2 antibody, 1110033K02Rik antibody, B230344N16 antibody, mKIAA0881 antibody, TAOK2 antibody, map3k17 antibody, psk antibody, psk1 antibody, tao1 antibody, tao2 antibody, TAO kinase 2 antibody, TAO kinase 2 L homeolog antibody, serine/threonine-protein kinase TAO2 antibody, TAOK2 antibody, Taok2 antibody, taok2.L antibody, taok2 antibody, LOC100085396 antibody
    背景
    In vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEKs) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK (Chen et al., 1999, Chen and Cobb, 2001). This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonists to the stress-responsive p38 MAPKs (Chen et al., 2003). Autophosphorylation of TAO may play a role in the mechanism of TAO activation. The MEK binding domain of TAO is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain. Anti-Phospho Ser181 TAO2 Western blot of rat cortex lysate showing specific immunolabeling of the ~120k TAO2 phosphorylated at Ser181 (Control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase: (-Ptase). The blot is identical to the control except that it was incubated in (-Ptase (1200 units for 30 min) before being exposed to the Ser181 TAO2 antibody. The immunolabeling is completely eliminated by treatment with (-Ptase.
    分子量
    '120 kDa
    基因ID
    9344
    UniProt
    Q9UL54
    途径
    Cell-Cell Junction Organization
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