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SYN1 抗体 (pSer62, pSer67)

This anti-SYN1 antibody is a 兔 多克隆 antibody detecting SYN1 in WB 和 ELISA. Suitable for 大鼠. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN361494
发货至: 中国

Quick Overview for SYN1 抗体 (pSer62, pSer67) (ABIN361494)

抗原

See all SYN1 抗体
SYN1 (Synapsin I (SYN1))

适用

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大鼠

宿主

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克隆类型

  • 109
  • 25
多克隆

标记

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This SYN1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    pSer62, pSer67

    特异性

    Specific for endogenous levels of the ~78 kDa synapsin I doublet phosphorylated at Ser62,67. Immunolabeling is blocked by preadsorption with the phosphopeptide used as antigen, but not by the corresponding non-phosphopeptide.

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    bovine, mouse

    产品特性

    Our Synapsin (Ser62,67) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects Synapsin (Ser62,67) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

    纯化方法

    Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

    免疫原

    Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser62/67 of rat synapsin, conjugated to keyhole limpet hemocyanin (KLH).

    亚型

    IgG
  • 应用备注

    Dilution Range: WB Brain: 1:1000

    Dilution Range: WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

    储存条件

    -20 °C

    储存方法

    Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

    有效期

    12 months
  • Chanaday, Vilcaes, de Paul, Torres, Degano, Roth: "Glutamate release machinery is altered in the frontal cortex of rats with experimental autoimmune encephalomyelitis." in: Molecular neurobiology, Vol. 51, Issue 3, pp. 1353-67, (2015) (PubMed).

    Leal-Ortiz, Waites, Terry-Lorenzo, Zamorano, Gundelfinger, Garner: "Piccolo modulation of Synapsin1a dynamics regulates synaptic vesicle exocytosis." in: The Journal of cell biology, Vol. 181, Issue 5, pp. 831-46, (2008) (PubMed).

    Tallent, Varghis, Skorobogatko, Hernandez-Cuebas, Whelan, Vocadlo, Vosseller: "In vivo modulation of O-GlcNAc levels regulates hippocampal synaptic plasticity through interplay with phosphorylation." in: The Journal of biological chemistry, Vol. 284, Issue 1, pp. 174-81, (2008) (PubMed).

  • 抗原

    SYN1 (Synapsin I (SYN1))

    别名

    SYN1

    背景

    Synonyms: Brain protein 4.1 antibody, SYN 1 antibody, SYN 1a antibody, SYN 1b antibody, SYN I antibody, SYN1 antibody, SYN1_HUMAN antibody, SYN1a antibody, SYN1b antibody, Synapsin 1 antibody, Synapsin I antibody, Synapsin-1 antibody, Synapsin1 antibody, SynapsinI antibody, SYNI antibody

    Description Logic: Our Synapsin (Ser62,67) rabbit polyclonal phosphospecific primary antibody is produced . It detects Synapsin (Ser62,67) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

    Gene Name Alternatives: SYN1

    分子量

    78 kDa

    基因ID

    281510

    UniProt

    P17599
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