Periostin 抗体
Quick Overview for Periostin 抗体 (ABIN361362)
抗原
See all Periostin (POSTN) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The antibody has been directly tested for reactivity in chicken, human, mouse and rat. Based on the homology of the immunogen with other species, we expect that this antibody will recognize periostin in most, if not all, species of mammals, birds, amphibians, and fishes. Specific for three periostin bands around ~93 kDa in mouse lung extract. The immunogenic peptide is present in all known splice variants of periostin and therefore this antibody recognizes all known molecular forms of periostin. The antibody also works well for immunohistochemistry on paraformaldehyde-fixed sections with a simple antigenretrieval protocol (incubate slides for 20 minutes at 90° C in 10 mM sodium citrate (pH 6.0)/ 0.1 % Tween-20).
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交叉反应
- 小鸡, 人, 小鼠
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预测反应
- most mammalian, avian, amphibian and fishes
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纯化方法
- Antigen Affinity Purified
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免疫原
- Synthetic peptide corresponding to amino acid residues from the fasciclin domain 1 of mouse periostin
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anti-Periostin (POSTN) (C-Term) antibody
POSTN 适用: 人 WB, ICC, IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 97-230) antibodyPOSTN 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 577-810) antibodyPOSTN 适用: 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 687-716), (C-Term) antibodyPOSTN 适用: 人, 大鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB18585 unconjugated
anti-Periostin (POSTN) (Middle Region) antibodyPOSTN 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, Cow, 犬, 马, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 24-836) antibodyPOSTN 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 193-326) antibodyPOSTN 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal unconjugated
anti-Periostin (POSTN) (AA 193-326) antibodyPOSTN 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal unconjugated
anti-Periostin (POSTN) (AA 24-173) antibodyPOSTN 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 193-326) antibodyPOSTN 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-649M unconjugated
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应用备注
- Recommended Dilution: WB: 1:1,000 IHC: 1:100 Quality Control: Western blots performed on each lot.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- ~ 0.5 mg/ml
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缓冲液
- 100 μL in PBS
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储存条件
- -20 °C
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- Periostin (POSTN)
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别名
- POSTN
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背景
- Periostin is a matricellular protein, i.e. an extracellular matrix protein that interacts both with other ECM proteins and with cell-surface receptors. Like many other matricellular proteins, the function of periostin is important both in embryonic development and in the remodeling of adult tissues in response to pathological insults. Periostin was originally isolated as an osteoblast-specific marker that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading (Kruzynska-Frejtag A. et al., 2004). Periostin has recently been shown to promote collagen fibrogenesis, inhibit differentiation of progenitor cells into cardiomyocytes and to be essential in maintaining the biomechanical properties of the adult myocardium (Norris et al., 2008).
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分子量
- '93 kDa
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基因ID
- 50706
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UniProt
- Q62009
抗原
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