Periostin 抗体 (C-Term)
Quick Overview for Periostin 抗体 (C-Term) (ABIN361361)
抗原
See all Periostin (POSTN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Specific for the ~93 kDa periostin doublet in mouse lung extract. This antibody does not recognize the single heart form of periostin or the lowest molecular weight form of lung periostin. Consistent with the fact that this antibody is made against an alternatively spliced region of periostin, this antibody recognizes a subset of the forms of periostin recognized on Western blots by the Pan periostin antibody (Catalog number 1622-PERI) and also shows a distinctive staining pattern by immunohistochemistry (data not shown). The antibody works well for immunohistochemistry on paraformaldehyde-fixed sections with a simple antigen-retrieval protocol (incubate slides for 20 minutes at 90° C in 10 mM sodium citrate (pH 6.0)/ 0.1 % Tween-20). The antibody is expected to work on all mammalian , avian species.
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交叉反应
- 小鸡, 人, 小鼠
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预测反应
- most mammalian and avian
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纯化方法
- Antigen Affinity Purified
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免疫原
- Bacterial fusion protein equivalent to a 188-amino acid polypeptide from the C-terminal region of mouse periostin which is comprised of six small alternatively-spliced exons
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anti-Periostin (POSTN) (C-Term) antibody
POSTN 适用: 人 WB, ICC, IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 97-230) antibodyPOSTN 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 577-810) antibodyPOSTN 适用: 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 687-716), (C-Term) antibodyPOSTN 适用: 人, 大鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB18585 unconjugated
anti-Periostin (POSTN) (Middle Region) antibodyPOSTN 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, Cow, 犬, 马, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 24-836) antibodyPOSTN 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 193-326) antibodyPOSTN 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal unconjugated
anti-Periostin (POSTN) (AA 193-326) antibodyPOSTN 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal unconjugated
anti-Periostin (POSTN) (AA 24-173) antibodyPOSTN 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 193-326) antibodyPOSTN 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-649M unconjugated
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应用备注
- Recommended Dilution: WB: 1:1,000 IHC: 1:100 Quality Control: Western blots performed on each lot.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 μL in PBS
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储存条件
- -20 °C
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- Periostin (POSTN)
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别名
- POSTN
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背景
- Periostin is a matricellular protein, i.e. an extracellular matrix protein that interacts both with other ECM proteins and with cell-surface receptors. Like many other matricellular proteins, the function of periostin is important both in embryonic development and in the remodeling of adult tissues in response to pathological insults. Periostin was originally isolated as an osteoblast-specific marker that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading (Kruzynska-Frejtag A. et al., 2004). Periostin has recently been shown to promote collagen fibrogenesis, inhibit differentiation of progenitor cells into cardiomyocytes and to be essential in maintaining the biomechanical properties of the adult myocardium (Norris et al., 2008) Anti-Periostin Western blot of rat lung lysate showing specific immunolabeling of the ~ 93 kDa periostin protein doublet.
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分子量
- '93 kDa
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基因ID
- 50706
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UniProt
- Q62009
抗原
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