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Actin 抗体

This anti-Actin antibody is a 小鼠 单克隆 antibody detecting Actin in WB, IHC 和 IF. Suitable for 小鸡. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN361349
发货至: 中国

Quick Overview for Actin 抗体 (ABIN361349)

抗原

See all Actin (ACTA1) 抗体
Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

适用

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小鸡

宿主

  • 86
  • 31
小鼠

克隆类型

  • 76
  • 38
  • 1
单克隆

标记

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This Actin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

克隆位点

C4
  • 特异性

    Specific for the ~42 kDa actin protein in lysates from skeletal, cardiac, gizzard and aorta tissues. Reacts with all actin isoforms.

    交叉反应

    所有种类

    纯化方法

    Ascites fluid

    免疫原

    Preparation of chicken gizzard actin

    亚型

    IgG1
  • 应用备注

    Recommended Dilution: WB:1:5,000 IF: 1:500 IHC: 1:500 Quality Control: Western blots performed on each lot.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascites fluid + 0.01 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Wheaton, Aten, Queiroz, Sullivan, Oberdick, Hoyt, Obrietan: "Circadian expression and functional characterization of PEA-15 within the mouse suprachiasmatic nucleus." in: The European journal of neuroscience, Vol. 47, Issue 7, pp. 845-857, (2019) (PubMed).

    Choi, Horning, Aten, Karelina, Alzate-Correa, Arthur, Hoyt, Obrietan: "Mitogen- and Stress-Activated Protein Kinase 1 Regulates Status Epilepticus-Evoked Cell Death in the Hippocampus." in: ASN neuro, Vol. 9, Issue 5, pp. 1759091417726607, (2018) (PubMed).

    Barcus, OLeary, Brockman, Rugowski, Liu, Garcia, Yu, Keely, Eliceiri, Schuler: "Elevated collagen-I augments tumor progressive signals, intravasation and metastasis of prolactin-induced estrogen receptor alpha positive mammary tumor cells." in: Breast cancer research : BCR, Vol. 19, Issue 1, pp. 9, (2017) (PubMed).

    Ramena, Yin, Yu, Walia, Elble: "CLCA2 Interactor EVA1 Is Required for Mammary Epithelial Cell Differentiation." in: PLoS ONE, Vol. 11, Issue 3, pp. e0147489, (2016) (PubMed).

    Barcus, Holt, Keely, Eliceiri, Schuler: "Dense collagen-I matrices enhance pro-tumorigenic estrogen-prolactin crosstalk in MCF-7 and T47D breast cancer cells." in: PLoS ONE, Vol. 10, Issue 1, pp. e0116891, (2016) (PubMed).

  • 抗原

    Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

    别名

    ACTA1

    背景

    Actin is the most abundant protein found in virtually all eukaryotic cells. It is also one of the most highly-conserved proteins, differing by no more than 20% in species as diverse as algae and humans, making it an excellent choice for use as a loading control. It is the monomeric subunit of microfilaments, one of the three major components of the cytoskeleton, and of thin filaments, which are part of the contractile apparatus in muscle cells. Thus, actin participates in many important cellular functions, including muscle contraction, cell motility, cell division and cytokinesis, vesicle and organelle movement, cell signaling, and the establishment and maintenance of cell junctions and cell shape. Anti-Actin Western blot of rat hippocampal homogenate showing specific immunolabeling of the ~ 42k actin protein.

    分子量

    '42 kDa

    基因ID

    421534

    UniProt

    P68139

    途径

    Caspase Cascade in Apoptosis, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
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