Angiotensin I Converting Enzyme 1 抗体
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Quick Overview for Angiotensin I Converting Enzyme 1 抗体 (ABIN360872)
抗原
See all Angiotensin I Converting Enzyme 1 (ACE) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes Mouse CD143. Other species not tested.
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纯化方法
- Protein A/G affinity chromatography
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免疫原
- Recombinant Angiotensin-Converting Enzyme (ACE, CD143) protein.
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亚型
- IgG2
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anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) (AA 1160-1306) antibody
ACE 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) (AA 651-864) antibodyACE 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IHC (fro), IF 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) (AA 814-1071) antibodyACE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) (AA 801-900) antibodyACE 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA, FACS, ICC, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) (AA 702-715), (Middle Region) antibodyACE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) (AA 592-701) antibodyACE 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4B10 unconjugated
anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) (AA 592-701) antibodyACE 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6A4 unconjugated
anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) antibodyACE 适用: 人 ELISA 宿主: 小鼠 Monoclonal 9B9 unconjugated
anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) (AA 30-270) antibodyACE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) (AA 30-182) antibodyACE 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3H7E4 unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.
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缓冲液
- 0.2 μm filtered PBS solution, None
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))
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别名
- ACE / CD143
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背景
- Angiotensin-converting enzyme or ACE2, may also called ACEH (ACE homologue), is an integral membrane protein and a zinc metalloprotease of the ACE family that also includes somatic and germinal ACE. Mouse ACE2 has about 40 % amino acid identity to the N-and C-terminal domains of mouse somatic ACE. The predicted mouse ACE 2 protein sequence consists of 798 amino acids, including a N-terminal signal peptide, a single catalytic domain, a C-terminal membrane anchor, and a short cytoplasmic tail. ACE 2 cleaves angiotensins I and II as a carboxypeptidase. ACE2 mRNA is found at high levels in testis, kidney and heart and at moderate levels in colon, small intestine and ovary. Classical ACE inhibitors such as captopril and lisinopril do not inhibit ACE2 activity. Novel peptide inhibitors of ACE2 do not inhibit ACE activity. Genetic data from Drosophila, mice and rats show that ACE2 is an essential regulator of heart function in vivo. In addition, ACE2 is a key SARSCoV Spike protein receptor in vivo and has a critical function in acute lung injury.Synonyms: Angiotensin-converting enzyme, DCP, DCP1, Dipeptidyl carboxypeptidase I
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基因ID
- 11421
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NCBI登录号
- NP_033728
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UniProt
- P09470
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途径
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
抗原
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