Lamin B2 抗体
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北京 101111
Quick Overview for Lamin B2 抗体 (ABIN360851)
抗原
See all Lamin B2 (LMNB2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Reacts with an epitope located in the C-terminal part of Lamin B2.
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纯化方法
- Purified
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免疫原
- Detergent insoluble fraction of potoroo cell line PtK1.
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亚型
- IgG1
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anti-Lamin B2 (LMNB2) antibody
LMNB2 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lamin B2 (LMNB2) (AA 341-620) antibodyLMNB2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lamin B2 (LMNB2) (AA 401-600) antibodyLMNB2 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2E2F4 unconjugated
anti-Lamin B2 (LMNB2) antibodyLMNB2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Lamin B2 (LMNB2) antibodyLMNB2 适用: 人 WB, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Lamin B2 (LMNB2) (Internal Region) antibodyLMNB2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lamin B2 (LMNB2) antibodyKD Validated LMNB2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2605 unconjugated Recombinant Antibody
anti-Lamin B2 (LMNB2) antibodyLMNB2 适用: 人, 小鼠 WB, IP 宿主: 小鼠 Monoclonal 8F6-E8-F12 unconjugated
anti-Lamin B2 (LMNB2) antibodyLMNB2 适用: 人, 小鼠, 非洲爪蟾, Hamster WB, IHC, FACS 宿主: 小鼠 Monoclonal LN43 unconjugated
anti-Lamin B2 (LMNB2) (AA 442-615) antibodyLMNB2 适用: 人 IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Suitable for Immunocytochemistry on Frozen Sections, Immunoblotting and FlowCytometry. Recommended Dilutions: 1/100-1/200 for Flow cytometry and for Immunohistochemistry with avidin-biotinylatedhorseradish peroxidase complex (ABC) as detection reagent.1/100-1/1000 for Immunoblotting applications.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS with 0.09 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store lyophilized at 2 - 8 °C and reconstituted at -20 °C.
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- Lamin B2 (LMNB2)
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别名
- Lamin-B2 (LMNB2)
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背景
- An important part of the cell nucleus is formed by nuclear lamina. Nuclear lamins form a network of filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel10, while the B-type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2. The nuclear lamins comprise a unique subclass of the intermediate filament protein family. They share a molecular domain organisation with the other intermediate filament proteins in that they are fibrous molecules that have an aminoterminal globular head, a central rod of a-helices and a carboxyterminal globular domain. Many biochemical and molecular features of lamins have been studied, but their functions remain still largely undetermined. One of the functions ascribed to the lamina is the maintenance of the structural integrity of the nucleus. Besides interactions with the nuclear membrane and other intermediate filaments, lamins interact with the nuclear chromatin. Eukaryotic chromatin is organised into loops, which are attached to the nuclear matrix. This organisation is thought to contribute to compaction of the chromatin and regulation of gene expression. Lamins, as part of the nuclear matrix, may be involved in these processes since chromatin binding sites have been detected in both A- and B-type lamins.Synonyms: LMN2, LMNB, LMNB-2, LMNB2, Lamin-B2, Nuclear Envelope Marker
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基因ID
- 84823
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NCBI登录号
- NP_116126
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UniProt
- Q03252
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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