PPP3CC 抗体 (N-Term)
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Quick Overview for PPP3CC 抗体 (N-Term) (ABIN360812)
抗原
See all PPP3CC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to PPP3CC.
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纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PPP3CC.
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亚型
- Ig Fraction
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- PPP3CC (Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC))
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别名
- PPP3CC / CALNA3
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背景
- Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha, calcineurin A-beta, and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95 % amino acid identity).Synonyms: CAM-PRP catalytic subunit, CNA3, Calcineurin testis-specific catalytic subunit, Calmodulin-dependent calcineurin A subunit gamma isoform, Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform, protein phosphatase 2B catalytic subunit gamma
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基因ID
- 5533
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NCBI登录号
- NP_005596
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UniProt
- P48454
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途径
- RTK signaling, WNT signaling, VEGF Signaling, BCR Signaling
抗原
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