PIK3 gamma 抗体 (C-Term)
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Quick Overview for PIK3 gamma 抗体 (C-Term) (ABIN360452)
抗原
See all PIK3 gamma (PIK3CG) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1073-1102, C-Term
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特异性
- This antibody reacts to PI3KCG.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This PI3KCG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1073~1102 amino acids from the C-terminal region of Human PI3KCG.
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亚型
- Ig Fraction
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应用备注
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ELISA: 1/1,000. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))
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别名
- PIK3CG
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背景
- PI3KCG belongs to the pi3/pi4-kinase family of proteins. This protein is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells.Synonyms: 5-bisphosphate 3-kinase catalytic subunit gamma isoform, PI3-kinase subunit gamma, PI3K-gamma, Phosphatidylinositol-4, PtdIns-3-kinase subunit p110-gamma, p120-PI3K
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基因ID
- 5294, 9606
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UniProt
- P48736
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途径
- PI3K-Akt Signaling, RTK signaling, AMPK Signaling, TLR signaling, Inositol Metabolic Process, Hepatitis C, VEGF Signaling
抗原
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