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PAK4 抗体 (N-Term)

The 兔 多克隆 anti-PAK4 antibody (ABIN360324) specifically detects PAK4 in WB, IHC (p) 和 EIA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN360324
发货至: 中国
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Quick Overview for PAK4 抗体 (N-Term) (ABIN360324)

抗原

See all PAK4 抗体
PAK4 (P21-Activated Kinase 4 (PAK4))

适用

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人, 小鼠

宿主

  • 70
  • 5
  • 1

克隆类型

  • 68
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多克隆

标记

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This PAK4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    This antibody reacts to PAK4.

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PAK4.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    PAK4 (P21-Activated Kinase 4 (PAK4))

    别名

    PAK4

    背景

    PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3, PAK4, PAK5, and PAK6. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton.Synonyms: KIAA1142, PAK 4, PAK-4, Serine/threonine-protein kinase PAK 4, p21-activated kinase 4

    基因ID

    10298, 9606

    UniProt

    O96013

    途径

    RTK signaling
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