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FKBP1A 抗体 (Middle Region)

This anti-FKBP1A antibody is a 兔 多克隆 antibody detecting FKBP1A in IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN360055
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for FKBP1A 抗体 (Middle Region) (ABIN360055)

抗原

See all FKBP1A 抗体
FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

适用

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宿主

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克隆类型

  • 46
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多克隆

标记

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This FKBP1A antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 12
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    Middle Region

    特异性

    This antibody reacts to FKBP12.

    纯化方法

    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human FKBP12.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Immunohistochemistry: 1/10 - 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

    别名

    FKBP1A / FKBP12

    背景

    FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.Synonyms: FK506-binding protein 1A, Immunophilin FKBP12, PPIase FKBP1A, Peptidyl-prolyl cis-trans isomerase FKBP1A, Rotamase

    基因ID

    2280, 9606

    UniProt

    P62942

    途径

    Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
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