Ret Proto-Oncogene 抗体 (N-Term)
Quick Overview for Ret Proto-Oncogene 抗体 (N-Term) (ABIN359926)
抗原
See all Ret Proto-Oncogene (RET) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-51, N-Term
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特异性
- This antibody recognizes Human RET (N-term).
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- KLH conjugated synthetic peptide between 21~51 amino acids from the N-terminal region of Human RET
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亚型
- Ig Fraction
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应用备注
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ELISA: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Ret Proto-Oncogene (RET)
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别名
- RET
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背景
- RET, a member of the cadherin superfamily, is one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This protein plays a crucial role in neural crest development, and the gene can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations i are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma.Synonyms: C-ret, CDHF12, Cadherin family member 12, Proto-oncogene tyrosine-protein kinase receptor ret
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基因ID
- 5979, 9606
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UniProt
- P07949
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途径
- RTK signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation
抗原
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