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RIPK3 抗体 (Middle Region)

This anti-RIPK3 antibody is a 兔 多克隆 antibody detecting RIPK3 in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN359363
发货至: 中国

Quick Overview for RIPK3 抗体 (Middle Region) (ABIN359363)

抗原

See all RIPK3 抗体
RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

适用

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人, 小鼠

宿主

  • 82
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克隆类型

  • 81
  • 16
多克隆

标记

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This RIPK3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 8
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    Middle Region

    特异性

    This antibody detects RIPK3 / RIP3.

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human RIPK3.

    亚型

    Ig Fraction
  • 应用备注

    ELISA1: 1,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

    别名

    RIPK3 / RIP3

    背景

    The product of the RIPK3 gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.Synonyms: RIP-3, RIP-like protein kinase 3, Receptor-interacting protein 3, Receptor-interacting serine/threonine-protein kinase 3

    分子量

    56901 Da.

    基因ID

    11035, 9606

    UniProt

    Q9Y572

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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