RIPK3 抗体 (N-Term)
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Quick Overview for RIPK3 抗体 (N-Term) (ABIN359362)
抗原
See all RIPK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 8-38, N-Term
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特异性
- This antibody detects RIPK3 / RIP3 at N-term.
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纯化方法
- Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region (between 8-38aa) of human RIPK3 / RIP3.
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亚型
- Ig Fraction
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应用备注
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ELISA 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
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别名
- RIPK3 / RIP3
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背景
- The product of the RIPK3 gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.Synonyms: RIP-3, RIP-like protein kinase 3, Receptor-interacting protein 3, Receptor-interacting serine/threonine-protein kinase 3
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分子量
- 56901 Da.
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基因ID
- 11035, 9606
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UniProt
- Q9Y572
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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