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Claudin 1 抗体 (Loop 1)

This anti-Claudin 1 antibody is a 兔 多克隆 antibody detecting Claudin 1 in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN358846
发货至: 中国

Quick Overview for Claudin 1 抗体 (Loop 1) (ABIN358846)

抗原

See all Claudin 1 (CLDN1) 抗体
Claudin 1 (CLDN1)

适用

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宿主

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克隆类型

  • 92
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多克隆

标记

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This Claudin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Loop 1

    特异性

    This antibody reacts to Claudin 1 (CLDN1).

    纯化方法

    Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Loop1 region of human CLDN1.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    Claudin 1 (CLDN1)

    别名

    Claudin-1 / CLDN1

    背景

    Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. CLDN1, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.Synonyms: CLD1, PRO944, SEMP1, Senescence-associated epithelial membrane protein, UNQ481

    基因ID

    9076, 9606

    UniProt

    O95832

    途径

    Cell-Cell Junction Organization, Hepatitis C
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