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NOTCH3 抗体 (C-Term)

This anti-NOTCH3 antibody is a 兔 多克隆 antibody detecting NOTCH3 in IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN358709
发货至: 中国

Quick Overview for NOTCH3 抗体 (C-Term) (ABIN358709)

抗原

See all NOTCH3 抗体
NOTCH3 (Notch 3 (NOTCH3))

适用

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宿主

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克隆类型

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多克隆

标记

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This NOTCH3 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    C-Term

    特异性

    This antibody reacts to NOTCH3.

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human NOTCH3.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    NOTCH3 (Notch 3 (NOTCH3))

    别名

    NOTCH3

    背景

    NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).Synonyms: Neurogenic locus notch homolog protein 3, Notch-3

    基因ID

    4854, 9606

    UniProt

    Q9UM47

    途径

    Notch Signaling
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