Insulin Receptor 抗体 (pTyr1185)
Quick Overview for Insulin Receptor 抗体 (pTyr1185) (ABIN358482)
抗原
See all Insulin Receptor (INSR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr1185
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特异性
- This antibody detects INSR pTyr1185. Predicted to cross react with Mouse (100 % Antigen Homology).
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纯化方法
- Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1185 of human INSR.
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亚型
- Ig Fraction
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anti-Insulin Receptor (INSR) antibody
INSR 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C7 unconjugated
anti-Insulin Receptor (INSR) (AA 1024-1298) antibodyINSR 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 1027-1364) antibodyINSR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 1101-1372) antibodyINSR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor (INSR) (C-Term) antibodyINSR 适用: 人, 小鼠, 大鼠, 犬, 猴, 马, Cow, 豚鼠, 兔, Pig, 小鸡, 绵羊, Hamster, Avian, Cat, 驴, 山羊 WB 宿主: 山羊 Polyclonal unconjugated
anti-Insulin Receptor (INSR) (C-Term) antibodyKO Validated INSR 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 51-150) antibodyINSR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 1325-1358) antibodyINSR 适用: 小鼠 WB 宿主: 兔 Polyclonal RB50340 unconjugated
anti-Insulin Receptor (INSR) (AA 1023-1298) antibodyINSR 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 27-57), (N-Term) antibodyINSR 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1421 unconjugated
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应用备注
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ELISA: 1/1,000. Dot Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Insulin Receptor (INSR)
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别名
- CD220 / INSR
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背景
- Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake, thereby mediating the metabolic functions of insulin. Binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). This protein can activate PI3K either directly by binding to the p85 regulatory subunit, or indirectly via IRS1. After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked.Synonyms: Insulin Receptor
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分子量
- 156307 Da
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基因ID
- 3643, 9606
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UniProt
- P06213
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途径
- NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
抗原
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