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E2F1 抗体 (pSer332)

E2F1 适用: 人 EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN358416
发货至: 中国
  • 抗原 See all E2F1 抗体
    E2F1 (E2F Transcription Factor 1 (E2F1))
    抗原表位
    • 24
    • 24
    • 20
    • 15
    • 15
    • 12
    • 10
    • 9
    • 8
    • 8
    • 8
    • 6
    • 6
    • 5
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    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer332
    适用
    • 210
    • 100
    • 56
    • 6
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 212
    • 13
    • 2
    克隆类型
    • 201
    • 26
    多克隆
    标记
    • 96
    • 17
    • 17
    • 13
    • 10
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    This E2F1 antibody is un-conjugated
    应用范围
    • 191
    • 101
    • 67
    • 66
    • 52
    • 31
    • 23
    • 22
    • 19
    • 18
    • 17
    • 14
    • 5
    • 2
    • 1
    Enzyme Immunoassay (EIA)
    特异性
    This antibody detects E2F1 pSer332.
    纯化方法
    Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S332 of human E2F1.
    亚型
    Ig Fraction
    Top Product
    Discover our top product E2F1 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Dot Blot: 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    E2F1 (E2F Transcription Factor 1 (E2F1))
    别名
    E2F1 (E2F1 产品)
    别名
    CG6376 antibody, DRTF1/E2F antibody, DmE2F-1 antibody, Dmel\\CG6376 antibody, Dp antibody, E(Sev-CycE)3A antibody, E(var)3-93E antibody, E(var)3-95E antibody, E(var)93E antibody, E2F antibody, E2F-1 antibody, E2F1 antibody, E2f1 antibody, Evar(3)164 antibody, dE2F antibody, dE2F1 antibody, dE2f antibody, dE2f1 antibody, de2f1 antibody, def21 antibody, drosE2F1 antibody, e2f antibody, e2f1 antibody, l(3)07172 antibody, l(3)j3B1 antibody, l(3)j3C2 antibody, l(3)rM729 antibody, RBAP1 antibody, RBBP3 antibody, RBP3 antibody, mKIAA4009 antibody, xE2F antibody, ATE2FB antibody, E2F TRANSCRIPTION FACTOR-1 E2F1 antibody, E2F transcription factor 1 antibody, E2FB antibody, E2FB TRANSCRIPTION FACTOR antibody, E2F transcription factor 1 antibody, E2F transcription factor 1 L homeolog antibody, E2f1 antibody, E2F1 antibody, e2f1.L antibody
    背景
    E2F1 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.Synonyms: E2F transcription factor 1, E2F-1, PBR3, PRB-binding protein E2F-1, RBBP3, Retinoblastoma-associated protein 1, Retinoblastoma-binding protein 3, Transcription factor E2F1
    分子量
    46920 Da
    基因ID
    1869, 9606
    UniProt
    Q01094
    途径
    p53 Pathway, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy
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