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PRKDC 抗体 (pThr2609)

PRKDC 适用: 人 EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN358415
发货至: 中国
  • 抗原 See all PRKDC 抗体
    PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
    抗原表位
    • 25
    • 13
    • 12
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr2609
    适用
    • 159
    • 91
    • 49
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 152
    • 20
    • 3
    • 2
    克隆类型
    • 148
    • 29
    多克隆
    标记
    • 93
    • 11
    • 11
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    This PRKDC antibody is un-conjugated
    应用范围
    • 85
    • 69
    • 58
    • 34
    • 32
    • 28
    • 27
    • 23
    • 14
    • 12
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Enzyme Immunoassay (EIA)
    特异性
    This antibody detects DNA pThr2609.
    纯化方法
    Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T2609 of human DNA- PK.
    亚型
    Ig Fraction
    Top Product
    Discover our top product PRKDC Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Dot Blot: 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
    别名
    DNA-PKcs / PRKDC / XRCC7 (PRKDC 产品)
    别名
    DNA-PKcs antibody, DNAPK antibody, DNPK1 antibody, HYRC antibody, HYRC1 antibody, XRCC7 antibody, p350 antibody, DNA-PKCS antibody, dna-pkcs antibody, dnapk antibody, dnpk1 antibody, hyrc antibody, hyrc1 antibody, prkdc-A antibody, xrcc7 antibody, PRKDC antibody, AI326420 antibody, AU019811 antibody, DNAPDcs antibody, DOXNPH antibody, dxnph antibody, p460 antibody, scid antibody, slip antibody, protein kinase, DNA-activated, catalytic polypeptide antibody, protein kinase, DNA-activated, catalytic polypeptide L homeolog antibody, DNA-dependent protein kinase catalytic subunit antibody, protein kinase, DNA activated, catalytic polypeptide antibody, PRKDC antibody, prkdc.L antibody, LOC100633457 antibody, Prkdc antibody
    背景
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Stem cell surface receptors and activate yeast MAPK pathway.Synonyms: DNA-dependent protein kinase catalytic subunit, DNPK1, HYRC, HYRC1, p460
    分子量
    469079 Da
    基因ID
    5591, 9606
    UniProt
    P78527
    途径
    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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