PRKDC 抗体 (pThr2609)
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北京 101111
Quick Overview for PRKDC 抗体 (pThr2609) (ABIN358415)
抗原
See all PRKDC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr2609
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特异性
- This antibody detects DNA pThr2609.
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纯化方法
- Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T2609 of human DNA- PK.
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亚型
- Ig Fraction
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anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (AA 4019-4128) antibody
PRKDC 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1B9 unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) antibodyPRKDC 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 3H6 unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) antibodyKD Validated PRKDC 适用: 人 WB, IF (p), FACS 宿主: 兔 Monoclonal 23GB2055 unconjugated Recombinant Antibody
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) antibodyPRKDC 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (C-Term) antibodyPRKDC 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (AA 151-300) antibodyPRKDC 适用: 人, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (C-Term) antibodyPRKDC 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (AA 3899-4128) antibodyPRKDC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (AA 4075-4104), (C-Term) antibodyPRKDC 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3465-3466 unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (pThr2647) antibodyPRKDC 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Dot Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
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别名
- DNA-PKcs / PRKDC / XRCC7
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背景
- Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Stem cell surface receptors and activate yeast MAPK pathway.Synonyms: DNA-dependent protein kinase catalytic subunit, DNPK1, HYRC, HYRC1, p460
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分子量
- 469079 Da
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基因ID
- 5591, 9606
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UniProt
- P78527
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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