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RPS6KA3 抗体 (pSer369)

This anti-RPS6KA3 antibody is a 兔 多克隆 antibody detecting RPS6KA3 in EIA. Suitable for 人.
产品编号 ABIN358394
发货至: 中国
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Quick Overview for RPS6KA3 抗体 (pSer369) (ABIN358394)

抗原

See all RPS6KA3 抗体
RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

适用

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宿主

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克隆类型

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多克隆

标记

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This RPS6KA3 antibody is un-conjugated

应用范围

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Enzyme Immunoassay (EIA)
  • 抗原表位

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    pSer369

    特异性

    This antibody detects RPS6KA3 pSer369. Predicted to cross react with Mouse and Zebrafish (100 % Antigen Homology).

    纯化方法

    Affinity purification in a 2-step procedure with the control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S369 of human RPS6KA3.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Dot Blot: 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

    别名

    RPS6KA3 / RSK2

    背景

    RSK3 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in the gene have been associated with Coffin-Lowry syndrome (CLS).Synonyms: ISPK-1, ISPK1, MAPKAPK-1b, MAPKAPK1, RSK-2, Ribosomal S6 kinase 2, Ribosomal protein S6 kinase alpha-3, S6K-alpha-3, p90RSK3

    分子量

    83736 Da

    基因ID

    6197, 9606

    UniProt

    P51812

    途径

    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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