DAAM1 抗体 (N-Term)
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Quick Overview for DAAM1 抗体 (N-Term) (ABIN357855)
抗原
See all DAAM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects DAAM1 (N-term). Predicted to cross react with Mouse (100 % Antigen Homology).
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纯化方法
- Protein A Chromatography followed by peptide affinity purification.
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human DAAM1.
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亚型
- Ig Fraction
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应用备注
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ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
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别名
- DAAM1
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背景
- Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton. Recent evidence suggests a role for the Formin homology (FH) proteins in these processes. DAAM1 contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by DAAM1, which is thought to function as a scaffolding protein.Synonyms: DAAM-1, Disheveled-associated activator of morphogenesis 1, FLJ41657, KIAA0666
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分子量
- 123473 Da
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基因ID
- 23002, 9606
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UniProt
- Q9Y4D1
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途径
- WNT signaling
抗原
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