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Ubiquilin 1 抗体 (N-Term)

The 兔 多克隆 anti-Ubiquilin 1 antibody is suitable to detect Ubiquilin 1 in samples from 人 和 小鼠. It has been validated for WB, IHC (p) 和 EIA.
产品编号 ABIN357617
发货至: 中国
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Quick Overview for Ubiquilin 1 抗体 (N-Term) (ABIN357617)

抗原

See all Ubiquilin 1 (UBQLN1) 抗体
Ubiquilin 1 (UBQLN1)

适用

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  • 1
  • 1
人, 小鼠

宿主

  • 50
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  • 1

克隆类型

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  • 5
多克隆

标记

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  • 1
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This Ubiquilin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 8
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    N-Term

    特异性

    This antibody is specific to Ubiquilin-1 (UBQLN1/PLIC1) (N-term).

    纯化方法

    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PLIC1.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry on paraffin sections: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    Ubiquilin 1 (UBQLN1)

    别名

    Ubiquilin-1 (UBQLN1)

    背景

    PLIC1 is an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer's and Parkinson's disease.Synonyms: DA41, PLIC-1, PLIC1, Protein linking IAP with cytoskeleton 1

    分子量

    62519 Da

    基因ID

    29979, 9606

    UniProt

    Q9UMX0
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