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SMURF1 抗体 (C-Term)

This anti-SMURF1 antibody is a 兔 多克隆 antibody detecting SMURF1 in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN357470
发货至: 中国
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Quick Overview for SMURF1 抗体 (C-Term) (ABIN357470)

抗原

See all SMURF1 抗体
SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))

适用

  • 52
  • 22
  • 3
人, 小鼠

宿主

  • 43
  • 10

克隆类型

  • 44
  • 9
多克隆

标记

  • 25
  • 6
  • 4
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SMURF1 antibody is un-conjugated

应用范围

  • 43
  • 31
  • 21
  • 11
  • 10
  • 6
  • 4
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 8
    • 8
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    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    C-Term

    特异性

    This antibody detects SMURF1 at C-term.

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of SMURF1.

    亚型

    Ig Fraction
  • 应用备注

    ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))

    别名

    SMURF1

    背景

    SMURF1 is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. This protein interacts with receptor-regulated SMADs specific for the BMP pathway, SMAD1 and SMAD5, in order to trigger their ubiquitination and degradation and thereby their inactivation.Synonyms: E3 ubiquitin-protein ligase SMURF1, KIAA1625, SMAD ubiquitination regulatory factor 1, SMAD-specific E3 ubiquitin-protein ligase 1, SMURF 1, SMURF-1

    分子量

    86113 Da

    基因ID

    57154, 9606

    UniProt

    Q9HCE7

    途径

    Regulation of Cell Size
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