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SLUG 抗体 (N-Term)

SNAI2 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN357448
发货至: 中国
  • 抗原 See all SLUG (SNAI2) 抗体
    SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
    抗原表位
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 50
    • 18
    • 14
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 39
    • 11
    克隆类型
    • 40
    • 9
    多克隆
    标记
    • 32
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This SLUG antibody is un-conjugated
    应用范围
    • 27
    • 20
    • 12
    • 9
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects SLUG at N-term.
    纯化方法
    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human SLUG.
    亚型
    Ig Fraction
    Top Product
    Discover our top product SNAI2 Primary Antibody
  • 应用备注
    ELISA 1: 1,000. Western blot 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Liang, Wang, Li, Yu, Zhang, Li: "miR-33a suppresses the nuclear translocation of ?-catenin to enhance gemcitabine sensitivity in human pancreatic cancer cells." in: Tumour biology, (2015) (PubMed).

    Huang, Chen, Chang, Yuan, Jeng: "Hepatocyte growth factor activates Wnt pathway by transcriptional activation of LEF1 to facilitate tumor invasion." in: Carcinogenesis, Vol. 33, Issue 6, pp. 1142-8, (2012) (PubMed).

    Collado, Thiede, Baker, Askew, Igbani, Corwin: "The postnatal accumulation of junctional E-cadherin is inversely correlated with the capacity for supporting cells to convert directly into sensory hair cells in mammalian balance organs." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 33, pp. 11855-66, (2011) (PubMed).

    Fu, Lv, Lin, Wu, Wang, Zhou, Zhang, Wang, Tsang, Zhu, Wang: "Ubiquitin ligase cullin 7 induces epithelial-mesenchymal transition in human choriocarcinoma cells." in: The Journal of biological chemistry, Vol. 285, Issue 14, pp. 10870-9, (2010) (PubMed).

    Bitoun, Oliver, Davies: "The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling." in: Human molecular genetics, Vol. 16, Issue 1, pp. 92-106, (2007) (PubMed).

    Gautier, Tietge, Boverhof, Perton, Le Guern, Masson, Rensen, Havekes, Lagrost, Kuipers: "Hepatic lipid accumulation in apolipoprotein C-I-deficient mice is potentiated by cholesteryl ester transfer protein." in: Journal of lipid research, Vol. 48, Issue 1, pp. 30-40, (2006) (PubMed).

  • 抗原
    SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
    别名
    SNAI2 / SLUG (SNAI2 产品)
    别名
    Slug antibody, Slugh antibody, Snail2 antibody, snail family transcriptional repressor 2 antibody, snail family zinc finger 2 antibody, Snai2 antibody
    背景
    SLUG is a member of the Snail family of C2H2-type zinc finger transcription factors. This protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in the gene encoding SLUG may be associated with sporadic cases of neural tube defects.Synonyms: Neural crest transcription factor Slug, Protein snail homolog 2, SLUGH, Zinc finger protein SNAI2
    分子量
    29986 Da
    基因ID
    6591, 9606
    UniProt
    O43623
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