SIGLEC7 抗体 (N-Term)
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- 抗原 See all SIGLEC7 抗体
- SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
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抗原表位
- N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SIGLEC7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects SIGLEC7 at N-term.
- 纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- 免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human SIGLEC7.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SIGLEC7 Primary Antibody
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anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 377-467) antibody
SIGLEC7 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 38-121) antibodySIGLEC7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (N-Term) antibodySIGLEC7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) antibody (PE)SIGLEC7 适用: 人 FACS 宿主: 小鼠 Monoclonal 6-434 PE
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) antibodySIGLEC7 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 18-353) antibodySIGLEC7 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 1-467) antibodySIGLEC7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H1 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) antibodySIGLEC7 适用: 人 FACS 宿主: 小鼠 Monoclonal 6-434 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 18-353) antibodySIGLEC7 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 1-30), (N-Term) antibodySIGLEC7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2711 unconjugated
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- 应用备注
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ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
- 别名
- CD328 / SIGLEC7 (SIGLEC7 产品)
- 别名
- SIGLEC7 antibody, AIRM1 antibody, CD328 antibody, CDw328 antibody, D-siglec antibody, QA79 antibody, SIGLEC-7 antibody, SIGLEC19P antibody, SIGLECP2 antibody, p75 antibody, p75/AIRM1 antibody, sialic acid-binding Ig-like lectin 7 antibody, sialic acid binding Ig like lectin 7 antibody, LOC468976 antibody, SIGLEC7 antibody
- 背景
- SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have one or more cytoplasmic immune receptor tyrosine-based inhibitory motifs (ITIM). SIGLECs are typically expressed on cells of the innate immune system, with the exception of the B-cell expressed SIGLEC6. Sequence analysis predicted that the 697-amino acid SIGLEC10 protein contains a signal peptide, an N-terminal V-set Ig-like domain and four C2-set Ig-like domains, five potential N-linked glycosylation sites, a transmembrane region, and a 126-residue cytoplasmic tail with 3 putative ITIMs. Northern blot analysis detected a major 3.0-kb SIGLEC10 transcript, with highest levels in spleen, lymph node, blood leukocytes, and appendix. Little or no expression was observed in pancreas, thyroid, and testis. Flow cytometric analysis demonstrated eosinophil-specific expression of SIGLEC10, but at a lower level than that of SIGLEC8. Expression was also detected on monocytes and a CD16-positive/CD56-negative natural killer-like lymphocyte population. After sialidase treatment, which is necessary for unmasking the sialic acid-binding site on SIGLECs interacting with cell surface sialic acids, cells expressing SIGLEC10 bound to red blood cells. Immunoprecipitation analysis indicated expression of a 100- to 120-kD monomeric protein, higher than the predicted molecular mass, suggesting that SIGLEC10 is glycosylated.Synonyms: AIRM1, Adhesion inhibitory receptor molecule 1, CDw328, D-siglec, QA79 membrane protein, Sialic acid-binding Ig-like lectin 7, Siglec-7, p75
- 分子量
- 51142 Da
- 基因ID
- 27036, 5874
- UniProt
- Q9Y286
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