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MCL-1 抗体 (BH3 Domain)

MCL1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN356822
发货至: 中国
  • 抗原 See all MCL-1 (MCL1) 抗体
    MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
    抗原表位
    • 24
    • 22
    • 16
    • 11
    • 9
    • 8
    • 8
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    BH3 Domain
    适用
    • 142
    • 78
    • 67
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 139
    • 8
    • 2
    • 1
    克隆类型
    • 134
    • 18
    多克隆
    标记
    • 70
    • 12
    • 11
    • 10
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This MCL-1 antibody is un-conjugated
    应用范围
    • 118
    • 66
    • 49
    • 44
    • 27
    • 26
    • 21
    • 20
    • 10
    • 8
    • 7
    • 4
    • 4
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody is specific to MCL1 (BH3 Domain).
    纯化方法
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    免疫原
    This antibody was developed against a synthetic peptide selected from the central region (BH3 domain) of human Mcl-1.
    亚型
    Ig Fraction
    Top Product
    Discover our top product MCL1 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS containing 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
    别名
    MCL1 (MCL1 产品)
    别名
    BCL2L3 antibody, EAT antibody, MCL1-ES antibody, MCL1L antibody, MCL1S antibody, Mcl-1 antibody, TM antibody, bcl2-L-3 antibody, mcl1/EAT antibody, AW556805 antibody, mcl-1 antibody, fb72f02 antibody, wu:fb70a08 antibody, wu:fb72f02 antibody, zfMLP1 antibody, zfMcl-1a antibody, zgc:109835 antibody, zgc:109763 antibody, E3 antibody, E3-2 antibody, RNE3 antibody, RNU107 antibody, SNORA63A antibody, elF-4AII antibody, MCL1, BCL2 family apoptosis regulator antibody, myeloid cell leukemia sequence 1 antibody, MCL1, BCL2 family apoptosis regulator a antibody, MCL1, BCL2 family apoptosis regulator b antibody, small nucleolar RNA, H/ACA box 63 antibody, MCL1 antibody, Mcl1 antibody, mcl1a antibody, mcl1b antibody, SNORA63 antibody
    背景
    The Mcl-1 protein belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.Synonyms: BCL2L3, Bcl-2-like protein 3, Bcl-2-related protein, EAT, Induced myeloid leukemia cell differentiation protein Mcl-1, mcl1/EAT, r004
    基因ID
    4170, 9606
    UniProt
    Q07820
    途径
    MAPK Pathway
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