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UBA3 抗体 (C-Term)

This 兔 多克隆 anti-UBA3 antibody specifically detects UBA3 in WB, IHC (p) 和 EIA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN356593
发货至: 中国
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Quick Overview for UBA3 抗体 (C-Term) (ABIN356593)

抗原

See all UBA3 抗体
UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))

适用

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人, 小鼠

宿主

  • 29

克隆类型

  • 26
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多克隆

标记

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This UBA3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 8
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    C-Term

    特异性

    This antibody is specific to UBE1C (C-term). Predicted to cross react with Mouse and DANRE (100 % Antigen Homology).

    纯化方法

    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human UBE1C.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blot: 1/100approx. 1/500. Immunohistochemistry: 1/50approx. 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))

    别名

    UBA3 / UBE1C

    背景

    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.Synonyms: NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1C, Ubiquitin-activating enzyme 3, Ubiquitin-activating enzyme E1C, Ubiquitin-like modifier-activating enzyme 3

    基因ID

    9039, 9606

    UniProt

    Q8TBC4
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