PINK1 抗体
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北京 101111
Quick Overview for PINK1 抗体 (ABIN356392)
抗原
See all PINK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody is specific to PINK1.
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产品特性
- Synonyms: PTEN-induced putative kinase protein 1, PARK6, BRPK, PINK-1, Serine/threonine-proteinkinase PINK1, mitochondrial, Parkinson disease (autosomal recessive) 6
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纯化方法
- Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- Recombinant PINK1 protein was used to produced this monoclonal antibody.
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亚型
- IgG1
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures. -
有效期
- 12 months
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- PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
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别名
- PINK1
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背景
- Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.Synonyms: BRPK, PARK6, PINK-1, PTEN-induced putative kinase protein 1, Parkinson disease (autosomal recessive) 6, Serine/threonine-protein kinase PINK1, mitochondrial
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基因ID
- 65018
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UniProt
- Q9BXM7
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途径
- Autophagy
抗原
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