SETD8 抗体 (N-Term)
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北京 101111
Quick Overview for SETD8 抗体 (N-Term) (ABIN356374)
抗原
See all SETD8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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特异性
- This antibody is specific SET07.
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产品特性
- Synonyms: SET8, PRSET7, PR-Set7, KMT5A, Histone-lysine N-methyltransferase SETD8, H4-K20-HMTaseSETD8, SET domain-containing protein 8, PR/SET domain-containing protein 07, LysineN-methyltransferase 5A
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纯化方法
- Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- This antibody was raised using purified recombinant GST fusion protein encoding theN-terminal region of human SET07.
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亚型
- IgG1
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anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 109-272) antibody
SETD8 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 7H1G10 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 109-272) antibodySETD8 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5E10F7 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (N-Term) antibodySETD8 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 小鼠 Monoclonal 43AT551-86 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (N-Term) antibodySETD8 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 43AT551-86 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 73-352) antibodySETD8 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 220-249) antibodySETD8 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB18964 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 136-258) antibodySETD8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) antibodySETD8 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) antibodySETD8 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) antibodySETD8 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
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别名
- SETD8 / SET07
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背景
- SET07 is a histone methyltransferase that methylates Lys-20 of histone H4. H4 Lys-20 methylation represents a specific tag for epigenetic transcriptional repression. The nuclear SET07 protein, which associates with silent chromatin on euchromatic arms but shows no association with constitutive heterochromatin, prefers nucleosomes as substrate compared to free histones. It appears that SET07 may play a role in maintaining silent chromatin by preventing neighboring acetylation of H4 tail. Although the SET domain contains the active site of enzymatic activity, both sequences upstream and downstream of the SET domain are required for methyltransferase activity.Synonyms: H4-K20-HMTase SETD8, Histone-lysine N-methyltransferase SETD8, KMT5A, Lysine N-methyltransferase 5A, PR-Set7, PR/SET domain-containing protein 07, PRSET7, SET domain-containing protein 8, SET8
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基因ID
- 387893
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UniProt
- Q9NQR1
抗原
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