MUC1 抗体
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北京 101111
Quick Overview for MUC1 抗体 (ABIN356308)
抗原
See all MUC1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
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This antibody is spescific for Epithelial Membrane Antigen (EMA).
Cellular Localization: Cytoplasmic, cell membrane. -
产品特性
- Synonyms: MUC-1, PEMT, Episialin, EMA, H23AG, PUM, DF3, CA 15-3, Polymorphic epithelial mucin,Tumor-associated mucin, Carcinoma-associated mucin, Tumor-associated epithelialmembrane antigen, Peanut-reactive urinary mucin, Breast carcinoma-associated antigenDF3
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免疫原
- Human milk fat globule membranes. Remarks: Epitope: DTRPMolecular weight of antigen: 260-400 kDa.
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亚型
- IgG1
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应用备注
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Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-FixedParaffin-Embedded (FFPE) tissue sections and cell smears)For IHC dilute concentared antibody at 1/50-1/100, use streptavidinapprox. biotin system orpolymer system, incubate 30 minutes at room temperature. Immunofluorescence. Recommended Positive Control: : Breast CA, colon CA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS, pH 7.4 containing 1 % BSA as stabilizer and 0.05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: One year from despatch. -
有效期
- 12 months
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- MUC1 (Mucin 1 (MUC1))
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别名
- CD227 / Mucin-1 / MUC1
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背景
- Epithelial Membrane Antigens are high molecular weight mucin-like glycoprotein. Antibodies to EMA have been shown to be useful as pan-epithelial markers for detection of early metastatic loci of carcinoma in the bone marrow or liver.Synonyms: Breast carcinoma-associated antigen DF3, CA 15-3, Carcinoma-associated mucin, DF3, EMA, Episialin, H23AG, MUC-1, PEMT, PUM, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin
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基因ID
- 4582
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UniProt
- P15941
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途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
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