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SUMO1 抗体

SUMO1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN350884
发货至: 中国
  • 抗原 See all SUMO1 抗体
    SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
    适用
    • 95
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    小鼠
    宿主
    • 100
    • 32
    • 3
    • 1
    • 1
    克隆类型
    • 93
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    多克隆
    标记
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    This SUMO1 antibody is un-conjugated
    应用范围
    • 112
    • 50
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    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    Specific for SUMO 1.
    交叉反应
    人, Marmoset, 小鼠, 大鼠
    交叉反应 (详细)
    Other species not yet tested.
    纯化方法
    IgG
    免疫原
    A synthetic peptide from mouse SUMO 1 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in human, rat and marmoset.
    亚型
    IgG
    Top Product
    Discover our top product SUMO1 Primary Antibody
  • 应用备注
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    有效期
    12 months
  • 抗原
    SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
    别名
    SUMO 1 (SUMO1 产品)
    背景
    Function: Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4 Subcellular location: Nucleus. Cytoplasm Post-translational modification: Cleavage of precursor form by SENP1 or SENP2 is necessary for function.,Ubiquitination,Small ubiquitin-related modifier 1, SUMO-1, Sumo1
    UniProt
    Q5I0H3
    途径
    M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway
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