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NGFR 抗体

This 小鼠 单克隆 anti-NGFR antibody specifically detects NGFR in WB, IHC 和 ELISA. The antibody is reactive with 大鼠 samples.
产品编号 ABIN350707
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for NGFR 抗体 (ABIN350707)

抗原

See all NGFR 抗体
NGFR (Nerve Growth Factor Receptor (NGFR))

适用

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大鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This NGFR antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 原理

    Mouse monoclonal antibody to rat p75NTR (MC192)

    特异性

    Specific for rat p75NTR.

    交叉反应

    大鼠

    纯化方法

    Affinity purified

    免疫原

    Nerve growth factor receptor (TNFR superfamily member 16)
  • 应用备注

    WB IHC ELISA. A working concentration of 5-15 μg,ml is recommended. This antibody is suitable for use in paraformaldehyde fixed alcohol fixed,paraffin-embedded sections. The optimal working solution should be determined by the end user.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

    注意事项

    Avoid freeze and thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

    有效期

    12 months
  • 抗原

    NGFR (Nerve Growth Factor Receptor (NGFR))

    别名

    p75NTR

    背景

    FUNCTION: Low affinity receptor which can bind to NGF BDNF NT-3 and NT-4. Can mediate cell survival as well as cell death of neural cells. SUBUNIT: Homodimer, disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with NGFRAP1/BEX3. Interacts with TRAF2 TRAF4 TRAF6 PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1. SUBCELLULAR LOCATION: Membrane, Single-pass type I membrane protein.

    途径

    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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