ATG4C 抗体
Quick Overview for ATG4C 抗体 (ABIN349989)
抗原
See all ATG4C 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Sheep antibody to ATG4C
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特异性
- Specific for ATG4C.
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交叉反应
- 人, 小鼠, 大鼠
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交叉反应 （详细）
- Other species not yet tested.
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纯化方法
- IgG
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免疫原
- A synthetic peptide from human cysteine protease ATG4C (autophagin-3 APG4C AUTL1 AUTL3) conjugated to an immunogenic carrier protein has been used as the antigen.
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亚型
- IgG
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anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 321-458) antibody
ATG4C 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E10H7 unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 419-448) antibodyATG4C 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (N-Term) antibodyATG4C 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 167-196) antibodyATG4C 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7497 unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 33-62), (N-Term) antibodyATG4C 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7561 unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 259-458) antibodyATG4C 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 1-458) antibodyATG4C 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 21-70) antibodyATG4C 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 419-448), (C-Term) antibodyATG4C 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7499 unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (N-Term) antibodyATG4C 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC WB. Use at a concentration of 10-50,micro,g,ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
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注意事项
- Avoid freeze and thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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有效期
- 12 months
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- ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))
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别名
- ATG4C
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背景
- Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation metamorphosis non-apoptotic cell death and aging. Reduced levels of autophagy have been described in some malignant tumors and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants encoding the same protein have been characterized. Cysteine protease required for autophagy which cleaves the C-terminal part of either MAP1LC3 GABARAPL2 or GABARAP allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II with a revealed C-terminal glycine is considered to be the phosphatidylethanolamine (PE)-conjugated form and has the capacity for the binding to autophagosomes. ENZYME REGULATION: Inhibited by N-ethylmaleimide. TISSUE SPECIFICITY: Highly expressed in skeletal muscle heart liver and testis.
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UniProt
- Q96DT6
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途径
- Autophagy
抗原
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