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Beclin 1 抗体

This anti-Beclin 1 antibody is a 绵羊 多克隆 antibody detecting Beclin 1 in WB 和 IHC. Suitable for 人.
产品编号 ABIN349986
发货至: 中国

Quick Overview for Beclin 1 抗体 (ABIN349986)

抗原

See all Beclin 1 (BECN1) 抗体
Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

适用

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宿主

  • 143
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绵羊

克隆类型

  • 139
  • 58
多克隆

标记

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This Beclin 1 antibody is un-conjugated

应用范围

  • 158
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 原理

    Sheep antibody to Beclin 1

    特异性

    Specific for Beclin-1.

    交叉反应

    人, Marmoset, 小鼠, 大鼠

    交叉反应 (详细)

    Other species not yet tested.

    纯化方法

    IgG

    免疫原

    A synthetic peptide from human Beclin-1 conjugated to blue carrier protein has been used as the antigen. The antigen is homologous in rat and mouse.

    亚型

    IgG
  • 应用备注

    IHC WB. Use at a concentration of 10-50,micro,g,ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

    注意事项

    Avoid freeze and thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

    有效期

    12 months
  • 抗原

    Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

    别名

    Beclin 1

    背景

    Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation metamorphosis non-apoptotic cell death and aging. Reduced levels of autophagy have been described in some malignant tumors and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. It may play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus. May play a role in autophagy. SUBCELLULAR LOCATION: Cytoplasm. Golgi apparatus membrane, Peripheral membrane protein. Note: Expressed in dendrites and cell bodies of cerebellar Purkinje cells TISSUE SPECIFICITY: Ubiquitous

    UniProt

    Q14457

    途径

    Autophagy
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