Beclin 1 抗体
Our Local Distributor
北京 101111
Quick Overview for Beclin 1 抗体 (ABIN7698499)
抗原
See all Beclin 1 (BECN1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Sheep antibody to Beclin 1
-
特异性
- Specific for Beclin-1.
-
交叉反应
- 人, Marmoset, 小鼠, 大鼠
-
交叉反应 (详细)
- Other species not yet tested.
-
纯化方法
- IgG
-
免疫原
- A synthetic peptide from human Beclin-1 conjugated to blue carrier protein has been used as the antigen. The antigen is homologous in rat and mouse.
-
亚型
- IgG
-
-
-
-
应用备注
- IHC WB. Use at a concentration of 10-50,micro,g,ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
-
注意事项
- Avoid freeze and thaw cycles.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
-
有效期
- 12 months
-
-
- Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
-
别名
- Beclin 1
-
背景
- Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation metamorphosis non-apoptotic cell death and aging. Reduced levels of autophagy have been described in some malignant tumors and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. It may play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus. May play a role in autophagy. SUBCELLULAR LOCATION: Cytoplasm. Golgi apparatus membrane, Peripheral membrane protein. Note: Expressed in dendrites and cell bodies of cerebellar Purkinje cells TISSUE SPECIFICITY: Ubiquitous
-
UniProt
- Q14457
-
途径
- Autophagy
抗原
-