SERPINB2 抗体 (Internal Region)
(1 reference)-
- 抗原 See all SERPINB2 抗体
- SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))
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抗原表位
- Internal Region
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适用
- 人, 猴
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SERPINB2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- This affinity-purified antibody is directed against human PAI-2 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. Reactivity occurs against human PAI-2 protein. A BLAST analysis was used to suggest cross reactivity with PAI-2 proteins from several primates based on 94% homology with the immunizing sequence. Reactivity against homologues from other sources is not known.
- 交叉反应
- 猴
- 产品特性
- Extracellular plasminogen activator inhibitor type-2 (also known as PAI-2, Placental plasminogen activator inhibitor, Monocyte Arg-serpin, Urokinase inhibitor, SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2) is a coagulation factor and a potent inhibitor of urokinase-type plasminogen activator (u-PA) and also acts as a multifunctional protein. It is present in most cells, especially monocytes and macrophages. PAI-2 exists in two forms, a 60-kDa, secreted, extracellular, glycosylated form and a 43-kDa intracellular form. It is a multifunctional protein that plays a role in cell differentiation, in prevention of programmed cell death, in the regulation of cell proliferation, in the inhibition of microbial proteinases and in the protection against stromal degradation. High levels of the PAI-2 protein are associated with a good prognosis in breast cancer, small cell lung, ovarian cancer, and inhibition of metastasis. PAI-2 also plays a role in inflammation on the surface of the eye. PAI-2 may cooperate with pRb2/p130 in modulating PAI-2 gene expression by chromatin remodeling.
- 纯化方法
- affinity purified
- 过滤
- Sterile filtered
- 免疫原
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This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to an internal area of human PAI-2 protein.
Immunogen Type: Peptide - 亚型
- IgG
- Top Product
- Discover our top product SERPINB2 Primary Antibody
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anti-Plasminogen Activator Inhibitor 2 (SERPINB2) antibody
SERPINB2 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (Center) antibodySERPINB2 适用: 人, 小鼠 WB, IP, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 154-408) antibodySERPINB2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A4 unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-100) antibodySERPINB2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 154-408) antibodySERPINB2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 293-389) antibodySERPINB2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-415) antibodySERPINB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (Internal Region) antibodySERPINB2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 170-393) antibodySERPINB2 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 116-144) antibodySERPINB2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB19097 unconjugated
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- 应用备注
- This affinity purified antibody has been tested for use in ELISA and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band 42-46.6 kDa in size corresponding to PAI-2 protein by western blotting in the appropriate cell lysate or extract.
- 说明
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Gene Name: SERPINB2
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.2 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is three (3) months from date of opening.
- 有效期
- 3 months
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: "Fibrinolytic Changes in Women with Preeclampsia." in: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, Vol. 28, pp. 10760296221126172, (2022) (PubMed).
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: "Fibrinolytic Changes in Women with Preeclampsia." in: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, Vol. 28, pp. 10760296221126172, (2022) (PubMed).
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- 抗原
- SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))
- 别名
- Plasminogen Activator Inhibitor 2 (SERPINB2 产品)
- 别名
- HsT1201 antibody, PAI antibody, PAI-2 antibody, PAI2 antibody, PLANH2 antibody, SERPINB2 antibody, Planh2 antibody, ovalbumin antibody, Pai2a antibody, serpin family B member 2 antibody, serpin peptidase inhibitor, clade B (ovalbumin), member 2 antibody, serine (or cysteine) peptidase inhibitor, clade B, member 2 antibody, SERPINB2 antibody, Serpinb2 antibody
- 物质类
- Amino Acid
- 背景
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Extracellular plasminogen activator inhibitor type-2 (also known as PAI-2, Placental plasminogen activator inhibitor; Monocyte Arg-serpin; Urokinase inhibitor; SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2) is a coagulation factor and a potent inhibitor of urokinase-type plasminogen activator (u-PA) and also acts as a multifunctional protein. It is present in most cells, especially monocytes and macrophages. PAI-2 exists in two forms, a 60-kDa, secreted, extracellular, glycosylated form and a 43-kDa intracellular form. It is a multifunctional protein that plays a role in cell differentiation, in prevention of programmed cell death, in the regulation of cell proliferation, in the inhibition of microbial proteinases and in the protection against stromal degradation. High levels of the PAI-2 protein are associated with a good prognosis in breast cancer, small cell lung, ovarian cancer, and inhibition of metastasis. PAI-2 also plays a role in inflammation on the surface of the eye. PAI-2 may cooperate with pRb2/p130 in modulating PAI-2 gene expression by chromatin remodeling.
Synonyms: PAI-2, Placental plasminogen activator inhibitor; Monocyte Arg-serpin; Urokinase inhibitor; SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 - 基因ID
- 5055, 4505595
- UniProt
- P05120
- 途径
- Autophagy
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